Not Just a Number: Why Estradiol Labs Don’t Tell the Full Story

If you’ve ever stared at your lab results, heart racing a little as you searched for the number you were told to expect—only to feel confused or even concerned when it wasn’t there—this newsletter is for you.

Lately, there’s been a wave of buzz online and in certain clinics claiming that unless your estradiol level hits a very specific number—typically 60 pg/mL—your hormone therapy isn’t “working.” That message is gaining momentum, and understandably, it’s causing some women to second-guess their progress, their prescriptions, and sometimes even their providers.

Let’s take a deep breath together. Then let’s untangle what’s helpful, what’s hype, and what your lab results actually mean for your care.

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